UbiProt Database - proteins_show

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Protein information

Protein name Ubiquitin carboxyl-terminal hydrolase 36 
Synonyms EC 3.1.2.15
Ubiquitin thioesterase 36
Ubiquitin-specific-processing protease 36
Deubiquitinating enzyme 36
Gene name USP36 , Synonym: KIAA1453 .
Source Homo sapiens (Human)
Expression system COS-7
Full length  1121
Precursor  no
Mature form length  1121
Molecular weight (Da)  122652
Swiss-Prot Sequence Version  January 23, 2007 (Sequence version 3)

Cross-references

Swiss-Prot/TrEMBL UBP36_HUMAN
PDB  

Ubiquitylation features

Ubiquitylation site  
 

Ubiquitylation type Multiple ubiquitylation
Features USP36 contains a PEST motif (sequence enriched in proline, glutamate, serine, and threonine, beleived to target proteins for rapid degradation).

Ubiquitylation/deubiquitylation machinery

E2 Not determined
E3 Not determined
E4/AP Not determined
DUB Not determined
Comments Ubiquitylation of USP36 protein was demonstrated by co-immunoprecipitation assay.

References

[1]Kim MS, Kim YK, Kim YS, Seong M, Choi JK, Baek KH.
Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated. Biochem Biophys Res Commun. 330(3):797-804 (2005).
[15809067]

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