UbiProt Database - proteins_show

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Protein information

Protein name Ubiquitin carboxyl-terminal hydrolase 
Synonyms EC 3.1.2.15
Gene name Dub1a .
Source Mus musculus (Mouse)
Expression system NIH3T3
Full length  465
Precursor  no
Mature form length  465
Molecular weight (Da)  51841
Swiss-Prot Sequence Version  July 5, 2004 (Sequence version 1)
Comments  JAK2 signaling is required for DUB-1A expression. Dub-1A gene contains a cytokine-inducible enhancer element.

Cross-references

Swiss-Prot/TrEMBL Q6X3X0_MOUSE
PDB  

Ubiquitylation features

Ubiquitylation site  
 

Ubiquitylation type Multiple ubiquitylation
Features Not determined

Ubiquitylation/deubiquitylation machinery

E2 Not determined
E3 Not determined
E4/AP Not determined
DUB Not determined
Comments Ubiquitylation of DUB-1A was demonstrated by co-immunoprecipitation experiments (Myc-tagged DUB-1A was coprecipitated with HA-tagged ubiquitin in NIH3T3 cells).

References

[1]Baek KH, Kim MS, Kim YS, Shin JM, Choi HK.
DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes. J Biol Chem. 279(4):2368-76 (2004).
[14583620]

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