UbiProt Database - proteins_show

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Protein information

Protein name Mating-type protein ALPHA2 
Synonyms MATalpha2 protein
Alpha-2 repressor
Gene name MATALPHA2 , ALPHA-2 , MAT2A , MATAL2 , YCR039C , YCR39C , HMLALPHA2 , YCL067C , YCL67C .
Source Saccharomyces cerevisiae (Baker's yeast)
Expression system Saccharomyces cerevisiae (Baker's yeast)
Full length  210
Precursor  no
Mature form length  210
Molecular weight (Da)  24282
Swiss-Prot Sequence Version  January 4, 2005 (Sequence version 2)


PDB 1AKH , 1APL , 1K61 , 1LE8 , 1MNM , 1YRN .

Ubiquitylation features

Ubiquitylation site  

Ubiquitylation type Not Determined
Features Not determined

Ubiquitylation/deubiquitylation machinery

E2 UBC6/UBC7-containing complex [2]
E3 Not determined
E4/AP Not determined
DUB Not determined
Comments in vivo [1]


[1]Hochstrasser M, Ellison MJ, Chau V, Varshavsky A:
The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo. Proc.Natl.Acad.Sci U.S.A 1991, 88:4606-4610.
[2]Chen P, Johnson P, Sommer T, Jentsch S, Hochstrasser M:
Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor. Cell 1993, 74:357-369.
[3]Richter-Ruoff B, Wolf DH, Hochstrasser M:
Degradation of the yeast MAT alpha 2 transcriptional regulator is mediated by the proteasome. FEBS Lett. 1994, 354:50-52.
[4]Laney JD, Hochstrasser M
Ubiquitin-dependent degradation of the yeast Mat(alpha)2 repressor enables a switch in developmental state. Genes Dev. 2003, 17:2259-2270.


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