UbiProt Database - proteins_show

UbiProt database V 1.0

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Protein information

Protein name NF-kappa-B inhibitor alpha 
Synonyms Major histocompatibility complex enhancer-binding protein MAD3
I-kappa-B-alpha
IkappaBalpha
IKB-alpha
Gene name NFKBIA , IKBA , MAD3 , NFKBI .
Source Homo sapiens (Human)
Full length  317
Precursor  no
Mature form length  317
Molecular weight (Da)  35609
Swiss-Prot Sequence Version  May 1, 1992 (Sequence version 1)

Cross-references

Swiss-Prot/TrEMBL IKBA_HUMAN
PDB 1IKN , 1NFI .

Ubiquitylation features

Ubiquitylation site  
 

Ubiquitylation type Not Determined
Features Not determined

Ubiquitylation/deubiquitylation machinery

E2 Not determined
E3 SCF(?-TrCP1)
E4/AP Not determined
DUB Not determined
Comments SCF(?-TrCP1) is a Cullin-RING ligase. Cullin component - Cul1, receptor - ?-TrCP1 and 2(FBW1, HOS)

References

[1]Petroski,M.D.; Deshaies,R.J.:
Function and regulation of cullin-RING ubiquitin ligases; Nat.Rev.Mol Cell Biol., 2005, 6, 1, 9-20
[15688063]

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