UbiProt Database - proteins_show

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Protein information

Protein name Cell division control protein 6 
Synonyms  
Gene name CDC6 , YJL194W .
Source Saccharomyces cerevisiae (Baker's yeast)
Expression system Saccharomyces cerevisiae (Baker's yeast)
Full length  513
Precursor  no
Mature form length  513
Molecular weight (Da)  58037
Swiss-Prot Sequence Version  February 1, 1995 (Sequence version 3)

Cross-references

Swiss-Prot/TrEMBL CDC6_YEAST
PDB  

Ubiquitylation features

Ubiquitylation site  
 

Ubiquitylation type Lys48-linked multi-ubiquitin chain
Features ND

Ubiquitylation/deubiquitylation machinery

E2 UBC3_YEAST [2]
E3 SCF(CDC4) [3,4]
E4/AP ND
DUB ND
Comments ND

References

[1]Petroski,M.D.; Deshaies,R.J.:
Function and regulation of cullin-RING ubiquitin ligases; Nat.Rev.Mol Cell Biol., 2005, 6, 1, 9-20
[15688063]
[2]Drury LS, Perkins G, Diffley JF.
The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J. 1997 Oct 1;16(19):5966-76.
[9312054]
[3]S?nchez M, Calzada A, Bueno A.
The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae. J Biol Chem. 1999 Mar 26;274(13):9092-7.
[10085159]
[4]Elsasser S, Chi Y, Yang P, Campbell JL.
Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis. Mol Biol Cell. 1999 Oct;10(10):3263-77.
[10512865]

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