UbiProt Database - proteins_show

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Protein information

Protein name Pheromone alpha factor receptor 
Gene name STE2 .
Source Saccharomyces cerevisiae (Baker's yeast)
Full length  431
Precursor  no
Mature form length  431
Molecular weight (Da)  47849
Swiss-Prot Sequence Version  November 1, 1988 (Sequence version 1)
Comments  Monoubiquitylation is sufficient for Ste2 endocytosis. Phosphorylation is required for ubiquitylation (Terrell et al., 1998).



Ubiquitylation features

Ubiquitylation site K337, K374

Ubiquitylation type Mono-ubiqutylation
Features Not determined

Ubiquitylation/deubiquitylation machinery

E2 Not determined
E3 Not determined
E4/AP Not determined
DUB Not determined
Comments Not determined


[1]Terrell J, Shih S, Dunn R, Hicke L.
A function for monoubiquitination in the internalization of a G protein-coupled receptor. Mol Cell. 1(2):193-202 (1998).
[2]Hicke L, Riezman H.
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84(2):277-87 (1996).


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