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Protein information

Protein name Pheromone alpha factor receptor 
Synonyms  
Gene name STE2 .
Source Saccharomyces cerevisiae (Baker's yeast)
Full length  431
Precursor  no
Mature form length  431
Molecular weight (Da)  47849
Swiss-Prot Sequence Version  November 1, 1988 (Sequence version 1)
Comments  Monoubiquitylation is sufficient for Ste2 endocytosis. Phosphorylation is required for ubiquitylation (Terrell et al., 1998).

Cross-references

Swiss-Prot/TrEMBL STE2_YEAST
PDB  

Ubiquitylation features

Ubiquitylation site K337, K374
 

Ubiquitylation type Mono-ubiqutylation
Features Not determined

Ubiquitylation/deubiquitylation machinery

E2 Not determined
E3 Not determined
E4/AP Not determined
DUB Not determined
Comments Not determined

References

[1]Terrell J, Shih S, Dunn R, Hicke L.
A function for monoubiquitination in the internalization of a G protein-coupled receptor. Mol Cell. 1(2):193-202 (1998).
[9659916]
[2]Hicke L, Riezman H.
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84(2):277-87 (1996).
[8565073]

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