UbiProt Database - proteins_show

UbiProt database V 1.0

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Protein information

Protein name T-cell surface glycoprotein CD4 
Synonyms T-cell surface antigen T4/Leu-3
T-cell differentiation antigen L3T4
Gene name Cd4 .
Source Mus musculus (Mouse)
Full length  457
Precursor  yes
Mature form length  431
Molecular weight (Da)  51297
Swiss-Prot Sequence Version  January 1, 1988 (Sequence version 1)

Cross-references

Swiss-Prot/TrEMBL CD4_MOUSE
PDB  

Ubiquitylation features

Ubiquitylation site  
 

Ubiquitylation type Not Determined
Features Not determined

Ubiquitylation/deubiquitylation machinery

E2 Not determined
E3 SCF(?-TrCP1)
E4/AP Not determined
DUB Not determined
Comments SCF(?-TrCP1) is a Cullin-RING ligase. Cullin component - Cul1, receptor - ?-TrCP1 and 2(FBW1, HOS). HIV Vpu also can serve as a receptor component of the ligase.

References

[1]Petroski,M.D.; Deshaies,R.J.:
Function and regulation of cullin-RING ubiquitin ligases; Nat.Rev.Mol Cell Biol., 2005, 6, 1, 9-20
[15688063]

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