UbiProt Database - proteins_show

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Protein information

Protein name Guanine nucleotide-binding protein G(T) gamma-T1 subunit  
Synonyms Transducin gamma chain
Gene name GNGT1 .
Source Bos taurus (Bovine)
Full length  73
Precursor  yes
Mature form length  70
Molecular weight (Da)  8413
Swiss-Prot Sequence Version  July 21, 1986 (Sequence version 1)

Cross-references

Swiss-Prot/TrEMBL GBG1_BOVIN
PDB 1AOR , 1B9X , 1B9Y , 1TBG , 2TRC .

Ubiquitylation features

Ubiquitylation site  
 

Ubiquitylation type Not Determined
Features Failure of a dominant negative UbcH7 to inhibit transducin beta-gamma ubiquitylation argues against an essential role for UbcH7 in transducin beta-gamma ubiquitylation, although data do not exclude the possibility that UbcH7 participates with UbcH5 in a combinatorial mechanism

Ubiquitylation/deubiquitylation machinery

E2 UbcH5 and UbcH7
E3 Not determined
E4/AP Not determined
DUB Not determined
Comments The primary recognition determinants for transducin beta-gamma ubiquitylation appear to reside on transducin beta. Transducin beta-gamma association with phosducin blocks transducin beta-gamma ubiquitylation and subsequent degradation. Transducin gamma species containin not more than four ubiquitin moieties, with monoubiquitylated species predominating

References

[1]Obin M, Lee BY, Meinke G, Bohm A, Lee RH, Gaudet R, Hopp JA, Arshavsky VY, Willardson BM, Taylor A
Ubiquitylation of the transducin beta gamma subunit complex: Regulation by phosducin. J.Biol.Chem. 2002, 277:44566-44575.
[12215439]

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